Alfie Mawson couldn't help Wycombe Wanderers create an upset in the First Round of the Capital One Cup as The Chairboys lost 1-0 away at Championship side Millwall.
The Lions settled the tie with a first-half goal from Matthew Briggs, who later saw red for two yellow cards, against the League Two side.
Alfie was substituted late on as Chairboys boss Gareth Ainsworth went searching for the equaliser.
Wycombe are next in action on Saturday in Sky Bet League Two at home to Carlisle.
Mark Smith was also in midweek action as he helped Hitchin Town to keep a clean sheet in their 3-0 win away at Banbury United in the Southern Premier League.
The 18-year-old made a number of crucial early saves before Hitchin took the lead after 25 minutes through Charlie Smith.
Simon Martin made it two just before half-time and the win was secured with Robbie Burns goal with 20 minutes to go.
The Canaries are back in league action on Saturday at home to Bideford.
Also out on loan is striker Will Grigg who was an unused substitute for MK Dons as they beat AFC Wimbledon 3-1 at Stadium:MK to set up a second-round tie with Manchester United.
The Dons next match is a trip to London Road to play Peterborough United in Sky Bet League One on Saturday.