Milton Keynes Dons set a new club record as they put seven past Oldham Athletic at Stadium:MK.
Will Grigg opened the scoring just after the quarter hour and Dean Bowditch made it two just before half-time.
Karl Robinson's side ran riot in the second-half with Grigg grabbing his second, and ninth of the season, four minutes after the break.
Alfie Potter made it four two minutes later before Dele Alli, Benik Afobe and Carl Baker struck in the final quarter hour to send MK into the Sky Bet League One top two.
In Sky Bet League Two Alfie Mawson and Wycombe Wanderers maintained a two point lead at the top after a 1-1 draw away at Accrington Stanley.
Paris Cowan-Hall put the Berkshire ahead in the ninth minute but the hosts equalised four minutes into the second-half to secure a share of the spoils.
Saturday was Alfie's 22nd appearance of the season with The Chairboys where he is on loan until January 1st.
Also in League Two Charlie Adams played 79 minutes as Stevenage secured their first win in five matches with a 1-0 success at home to Exeter City.
Boro arrested their slip down the League Two table as Charlie Lee scored with six minutes to go to move Stevenage up to 13th in League Two, six points off the play-off places.
Charlie has made 11 appearances for Stevenage in his time in Hertforshire which runs into the beginning of 2015.
In the Vanarama Conference Aldershot Town slipped to a 3-1 defeat at Welling United as they dropped down to 18th in the table.
Emmanuel Oyeleke was an unused substitute as Tyrone Marsh's double and a Kieron St Aimie goal secured the points for Welling despite Glenn Wilson making it 2-1 midway through the second-half.
Lower down the league ladder Mark Smith and Hampton & Richmond Borough went down 2-1 at home to Billericay Town to fall for a third straight defeat.
Richard Halle put the Essex side ahead midway through the first-half before former Bee Glenn Poole settled matters with 11 minutes to go.
Tom Collins pulled one back in injury time but it wasn't enough as Borough dropped to 18th in the Ryman Premier League.
Stourbridge fell to a 1-0 defeat away at Whitby Town with Steven Snaith scoring the decisive goal in the 93rd minute.
Kieran Morris was absent from the team as The Glassboys dropped to 10th in the league table following the defeat.