Brentford will face Plymouth Argyle in the third round of the FA Cup.
The Bees will host Wayne Rooney's side at Gtech Community Stadium on Saturday 11 January (3pm kick-off).
Thomas Frank's side and Argyle both entered at this stage of the competition alongside their fellow Premier League and Championship clubs respectively.
Plymouth, who are in their second season in the second tier, currently sit 21st in the table, two points above the relegation zone.
Ticket information will follow in due course.
FA Cup third-round draw in full
Southampton v Swansea City
Arsenal v Manchester United
Exeter City v Oxford United
Leyton Orient v Derby County
Reading v Burnley
Aston Villa v West Ham
Norwich City v Brighton & Hove Albion
Manchester City v Salford
Millwall v Dagenham & Redbrige
Liverpool v Accrington Stanley
Bristol City v Wolverhampton Wanderers
Preston North End v Charlton Athletic
Chelsea v Morecambe
Middlesbrough v Blackburn Rovers
Bournemouth v West Bromwich Albion
Mansfield Town v Wigan Athletic
Tamworth v Tottenham
Hull City v Doncaster Rovers
Sunderland v Stoke City
Leicester City v Queens Park Rangers
Brentford v Plymouth Argyle
Coventry City v Sheffield Wednesday
Newcastle United v Bromley
Everton v Peterborough United
Wycombe Wanderers v Portsmouth
Birmingham City v Lincoln City
Leeds United v Harrogate Town
Nottingham Forest v Luton Town
Sheffield United v Cardiff City
Ipswich Town v Bristol Rovers
Fulham v Watford
Crystal Palace v Stockport County