Both teams have been confirmed at Turf Moor, with Brentford making two changes from the last Premier League outing.
David Raya was ruled out for four or five months with a knee injury last week, meaning a start for Álvaro Fernández in goal. Marcus Forss also comes into Thomas Frank's side with Bryan Mbeumo still recovering from an injury, the Frenchman does make the bench though.
Brentford: Fernández; Zanka, Jansson (c), Pinnock; Canós, Jensen, Nørgaard, Onyeka, Henry; Forss, Toney
Subs: Cox (GK), Goode, Ghoddos, Mbeumo, Fosu, Janelt, Bidstrup, Roerslev, Stevens
Burnley: Pope; Lowton, Tarkowski, Mee (c), Taylor; Gudmundsson, Brownhill, Westwood, McNeil; Wood, Cornet
Subs: Hennessey (GK), Cork, Barnes, Lennon, Rodriguez, Collins, Pieters, Bardsley, Vydra