Brentford will face fellow Premier League side West Ham United away in the fifth round of the FA Cup.
The Bees progressed from the fourth round following a hard-fought 1-0 victory against National League North side Macclesfield.
West Ham defeated Championship side QPR at home in the third round before edging past League One outfit Burton Albion on Saturday lunchtime.
London Stadium will host the tie on the weekend of Saturday 7 March.
FA Cup fifth-round draw
Fulham v Southampton
Leeds United v Norwich City
Mansfield Town v Arsenal
Newcastle United v Manchester City
Port Vale or Bristol City v Sunderland
West Ham United v Brentford
Wolverhampton Wanderers v Liverpool
Wrexham v Chelsea